Evidence of the ability of inflammation to both initiate and fuel cancer has been accumulating since at least the 1980s. In fact, any chronic inflammatory disease – such as arthritis, bronchitis, fasciitis, colitis, and asthma – can increase the risk of cancer. For example, according to a 2000 study, approximately one in every ten patients with ulcerative colitis will eventually develop colorectal cancer. However, it isn’t just the risk of cancer that is a concern when chronic inflammation is present. A study published in the May 2009 issue of the Journal of Clinical Oncology demonstrated that patients with high blood levels of C-reactive protein (CRP) and serum amyloid A (SAA) were two to three times more likely to die prematurely or have their cancer return than patients with lower levels.
These markers indicate the presence of inflammation in the body. While acute inflammation is a healthy immune system response, chronic inflammation is not. Inflammation is one of the mechanisms that initiate the cascade of molecular events that lead to cancer and promote the growth of existing tumors. If a cellular mutation is the spark that lights the malignant fire, then inflammation is the fuel that keeps the fire growing. In general, the higher your CRP levels, the more unfavorable your prognosis. Indeed, in advanced cancers, CRP levels are often the most reliable indicator of prognosis, particularly with colorectal, lung, pancreatic, and prostate cancers.
The converse is also true: controlling inflammation can reduce the risk of and decrease the aggressiveness of cancer. Most, if not all patients, are dealing with high levels of inflammatory biochemicals that are produced by malignancies, and increased by surgery, radiation and chemotherapy. At the Block Center, we measure and monitor the inflammation levels of all of our patients, and encourage them to make lifestyle and dietary changes that can significantly minimize other sources of inflammation. It is important to note that being overweight, especially with excess abdominal fat, can be particularly harmful. People who are overweight have a higher level of inflammatory compounds in their blood, regardless of lifestyle or medical history.
Because refined carbs and other high glycemic-index foods are directly related to blood levels of
C- reactive protein, the Life Over Cancer diet emphasizes whole grains, legumes, vegetables, and fruit. Artichokes, spinach, broccoli, sweet potatoes, cucumbers, tomatoes, onions, parsley and zucchini are especially good anti-inflammatory vegetables; eat brightly colored fruits like cherries, blackberries, blueberries, and strawberries.
Here are a few lifestyle changes Dr. Block recommends: Get adequate sleep – sleeping less than four hours a night for ten straight nights can make levels of C-reactive protein soar – avoid unhealthy high-flame or high-heat cooking methods like charcoal grilling and deep frying, limit alcohol consumption, and if you smoke – quit!
For more information on The Block Center for Integrative Cancer Treatment, visit BlockMD.com.
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